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Study Participants Needed: Immune Response in Celiac Disease on In-vitro Gluten Challenge

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8/30/2013

The below text is from the study listing on ClinicalTrials.gov.

Purpose: The main purpose of this study is to see how cells taken from the lining of the intestine behave in the laboratory with exposure to gluten and other substances that act on the immune system. The cells lining the intestine of a person with celiac disease should be different than a person without celiac disease. The study doctors would like to see how the cells react after coming in contact with gluten and if substances that act on the immune system can prevent gluten related inflammation. Examples of these substances include steroids. The cells should produce chemicals of their own in response to the gluten. These other chemicals will be measured and the results compared between those with:

  • celiac disease that does not respond to a gluten-free diet (refractory celiac disease)
  • celiac disease which is controlled by a gluten-free diet
  • uncontrolled celiac disease (either newly diagnosed with celiac disease or not on a gluten-free diet
  • gluten-sensitivity
  • disorders other than celiac disease.

Location: Beth Israel Deaconess Medical Center (BIDMC), Boston, MA 02215

Study Sponsor: Beth Israel Deaconess Medical Center

Visit ClinicalTrials.gov to view the full study description and learn more about how to get involved.

Note: NFCA maintains the position that views and information presented on articles and websites we link to are those of the authors, and not necessarily those of NFCA.
 

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